3D Printed Osteochondral Scaffold With Biomimetic Structure

Customizable 3D printed GelMA-PEGDA scaffolds with biphasic TPNPs and nHA distributions structure were prepared successfully. The scaffolds provided an excellent platform for hMSC proliferation and osteochondral differentiation. The most significant improvement in chondrogenic gene (Col II D1, Sox-9, Aggrecan) and osteogenesis gene (Col I, Osteocalcin, OPN, Runx-2, ALP) expressions were observed on the 3D scaffolds. This study demonstrated that customizable 3D printed scaffolds are excellent candidates for promoting osteochondral differentiation of hMSCs, thus promising for future osteochondral regenerative medicine applications.

The poster is here: L0K18004-3D Printed Osteochondral Scaffold With Biomimetic Structure.pdf