Integrating Electrospun Microfibers into 3D Printed Scaffolds for Nerve Regeneration

This study demonstrated a novel approach for creating neural scaffold using a combination of SL 3D printing and electrospinning techniques. The resultant scaffold exhibited 3D printed microporous channels embedded with PCL or PCL/gelatin electrospun fibers. The incorporation of electrospun fibers into the 3D constructs result in enhanced mechanical properties. In addition, it was found that 3D printed scaffolds with PCL/gelatin fibers enhanced the neural stem cell differentiation compared to scaffolds with PCL alone fibers. Furthermore, a highly aligned PCL/gelatin fibers within the 3D printed scaffold improved the neurite outgrowth and directional control of primary cortical neurons.

The poster is here: L0K19001-Integrating Electrospun Microfibers into 3D Printed Scaffolds for Nerve Regeneration.pdf